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Airdate: October 8, 2009
When Thatcher, Meredith and Lexie's father, returns to the hospital with a failed liver, it's up to Meredith to save his life. Meanwhile, Izzie empathizes with a patient riddled with tumors, as Mark, annoyed with Cristina's competitive zeal, tricks her into assisting on an unusual surgery. Guest starring is Jeff Perry as Thatcher Grey, Ralph Waite as Irving Waller, Tom Amandes as Charlie Waller, Isabella Hofmann as Irene Waller, Jocko Sims as Randy and Kristen Ariza as Angela.